Prion disease

research progress on prion and prion disease therapy

朊病毒和朊病毒疾病治疗的研究进展

Could RNA interfere with prion disease?

RNA能否干预普粒子疾病?

【 Objective 】 The purpose of this study is to clarify the structural features of artiodactyl PrP gene, relationships of the sequence variations with its structure-function and the species barrier of prion disease transmission, and molecular phylogeny among the PrP genes.

目的为明了偶蹄动物PrP基因的结构特征及其变异与结构、功能和朊粒病传染种间屏障的关系以及系统发生关系；

central to the pathogenesis of all forms of prion disease is the prion protein.

中央的发病机制中的一切形式的朊病毒疾病的朊蛋白。

when these mri findings are observed in an appropriate clinical context, the diagnosis of prion disease is very likely.

当这些MRI表现是在一个适当的观察临床方面，朊病毒疾病的诊断是非常可能的。

cytokines related to prion disease

朊蛋白病相关的细胞因子

Kuru is a prion disease related to Creutzfeldt-Jakob Disease ( CJD) in humans and bovine spongiform encephalopathy ( mad cow disease).

库鲁病是一种与库兹菲德-雅各氏症和疯牛病有关的朊病毒疾病。

Mad cow disease is caused by the misfolding of a small protein called Prion.

该病与羊瘙痒病具有同源性,它们与人类克-雅氏病(Creutzfeldt-Jakobdisease, CJD) 均是海绵状脑组织病变,由Prion蛋白引起.

we have shown an initial proof of this principle by following the evolution of prion disease in mice.

我们藉由追踪实验小鼠体内普恩蛋白疾病的进展，对这个理论有了初步的验证。

surgeon or designee will notify the operating room of the brain biopsy of suspected prion disease.

外科医生或操作者应通知可疑朊毒体病人进行脑组织活检的手术室。